Impact Protein Precipitation Information

Impact™ protein precipitation plates with Solvent Shielding Technology™ offer a rapid and convenient way to remove proteins from plasma and tissue homogenate samples prior to analysis. The Solvent Shielding Technology design will withhold organic solvents above the filter membranes for up to 25 minutes, allowing for direct in-well precipitation upon sample addition. The precipitate is then filtered out via vacuum, centrifuge or positive pressure resulting in a clean, protein depleted extract.

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Process plasma and tissue homogenate samples
Precipitate with acetonitrile or methanol
Square well design that is compatible with common vacuum manifolds and automated workstations
2 mL well for large and small volume samples

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How to Improve Sample Preparation Accuracy, Reproducibility, and Lab-to-Lab Variation with Automation

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<p style="cursor: auto;">Impact™ protein precipitation plates with Solvent Shielding Technology™ offer a rapid and convenient way to remove proteins from plasma and tissue homogenate samples prior to analysis. The Solvent Shielding Technology design will withhold organic solvents above the filter membranes for up to 25 minutes, allowing for direct in-well precipitation upon sample addition. The precipitate is then filtered out via vacuum, centrifuge or positive pressure resulting in a clean, protein depleted extract.</p>

<p style="cursor: auto;"><strong style="cursor: auto;">Discover the Impact Advantage</strong></p>

<ul style="cursor: auto;">
	<li style="cursor: auto;">Process plasma and tissue homogenate samples</li>
	<li style="cursor: auto;">Precipitate with acetonitrile or methanol</li>
	<li style="cursor: auto;">Square well design that is compatible with common vacuum manifolds and automated workstations</li>
	<li style="cursor: auto;">2 mL well for large and small volume samples</li>
</ul>

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<p><a href="http://www.chromatographyonline.com/lcgc/Features/How-to-Improve-Sample-Preparation-Accuracy-Reprodu/ArticleStandard/Article/detail/813507">How to Improve Sample Preparation Accuracy, Reproducibility, and Lab-to-Lab Variation with Automation</a></p>

<p style="padding-top: 10px; cursor: auto;"><strong style="cursor: auto;">Don't forget the accessories!</strong></p>

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	<li style="cursor: auto;"><a href="http://www.phenomenex.com/Products/Search/Accessories?partNo=collection%20plates&cookie=false" style="cursor: pointer;">Collection Plates »</a></li>
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	<li><a href="/Products/SPDetail/presston">Positive Pressure Manifold »</a></li>
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Featured

BROCHURE

Finally, An Easier Solution for Protein Precipitation

Simplify your protein precipitation with Impact Protein Precipitation Plates.
VIDEO

See How Impact Simplifies Protein Precipitation

View a short animation that demonstrates how Impact can simplify your protein preciptaiton.
TECHNICAL NOTE

Rapid Removal of ß-Glucuronidase from Hydrolyzed Urine Samples

Greatly extend column column lifetime by following a simple, automatable procedure to remove ß-glucuronidase from hydrolyzed urine samples.
TECHNICAL NOTE

Simple and Fast Quantitation of Vitamin B3

Following a rapid, automatable protein precipitation, nicotinic acid and nicotinamide are analyzed by LC/MS/MS down to an LOD of 2 ng/mL.

Technical Documents
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Document Type:

Document Type	Title
Other	Clinical Research Solutions Guide	Add to My Documents
Brochures	Custom Method Development and Optimization Services for Clinical Research	Add to My Documents
Technical Notes	Effective Sample Preparation and LC-MS/MS Analysis of Unconjugated Bile Acids from Human Serum Using Impact PPT and Kinetex 2.6µm Polar C18 (TN-1217)	Add to My Documents
Brochures	Finally, an Easier Protein Precipitation Solution	Add to My Documents
Webinar	Overcoming the Challenges of Sample Preparation and LC/MS/MS Method Development for Clinical Applications	Add to My Documents
Other	Pain Panel/Pain Management Drugs Applications Guide	Add to My Documents
Other	Sample Preparation Selection and Users Guide	Add to My Documents
Webinar	How to Determine the Best Sample Preparation Technique for your Unique Samples	Add to My Documents
Other	THE Clinical Application Notebook, Volume 1	Add to My Documents
Brochures	Upgrade Your Pain Management Drug Testing	Add to My Documents
Other	Vitamin Testing Applications Guide	Add to My Documents
Technical Notes	25-OH Vitamin D2 and D3 from Serum by LC/MS/MS (TN-1055)	Add to My Documents
Technical Notes	Automated Solution for Post Hydrolysis Enzyme Removal and LC/MS/MS Analysis of Illicit and Pain Related Compounds from Urine (TN-0093)	Add to My Documents
Technical Notes	Beta Glucuronidase Removal (TN-0060)	Add to My Documents
Technical Notes	Beta-Glucuronidase Removal from Hydrolyzed Pain Management Urine Samples (TN-0083)	Add to My Documents
Supporting Docs	How to Improve Sample Preparation Accuracy, Reproducibility, and Lab-to-Lab Variation with Automation	Add to My Documents
Technical Notes	Nicotinic Acid and Nicotinamide in Human Plasma by LC/MS/MS (TN-1151)	Add to My Documents
Technical Notes	Thiamine Monophosphate (TMP) and Thiamine from Human Breast Milk (TN-0062)	Add to My Documents
Other	Validation of an Automated Method to Remove Beta-Glucuronidase from Hydrolyzed Pain Management Urine Samples	Add to My Documents
Other	Vitamin Testing Application Guide	Add to My Documents
Supporting Docs	Collection Plate and Sealing Mat Selection Guide	Add to My Documents
Supporting Docs	Protein Precipitation Protocol	Add to My Documents
Supporting Docs	Declaration of Conformity	Add to My Documents

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Rapid Protein Precipitation

Impact Protein Precipitation Information

Featured

Finally, An Easier Solution for Protein Precipitation

See How Impact Simplifies Protein Precipitation

Rapid Removal of ß-Glucuronidase from Hydrolyzed Urine Samples

Simple and Fast Quantitation of Vitamin B3